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Defense Intelligence Reference Document Technological Approaches To Controlling

Defense Intelligence Agency · 36 pages · text from the file's own layer

This Defense Intelligence Reference Document from the Defense Intelligence Agency, dated 23 March 2010, was produced under the Advanced Aerospace Weapon System Applications (AAWSA) Program. It surveys invasive and noninvasive brain-machine interface technologies for controlling external devices without limb-operated interfaces. The technologies covered include EEG, MEG, fMRI, NIRS, and implanted electrode arrays. It concludes that noninvasive electrical monitoring is the most promising near-term approach. In the long term, it favors invasive single-neuron cortical connections that use optical stimulation or chip-based arrays.

  • p. 5 UNCLASSIFIED/)' Pett :SPPll!ltllt '11815 .,.LY Technological Approaches to Controlling External Devices in the Absence of…
  • p. 8 …Neurons require some time to reset between firings, nominally the duration of the pulse for that…
  • p. 10 UNCLASSIFIED/ ,erg A gffllil.t.L '1181!! 8HLY The brain activity mentioned above is a complex…
  • p. 13 …The response time to execute a command using these systems is measured in seconds. The results…
  • p. 14 …application, the fact that 100 IT is about 100 million times smaller than the Earth's…
  • p. 15 …In current MRis, these gradient fields are produced with electromagnets, and the series of time-dependent…
  • p. 18 …prior to implantation, and then the tasks are repeated multiple times while muscle action and cortical…
  • p. 19 …the movement control algorithm is similar to a population vector in that movement at each time…
  • p. 20 UNCLASSIFIED/,'P81il 8PPll!ltllt ~81!! 8HLV Japan in real time. Using visual feedback to the monkey…
  • p. 21 …employed to allow for real-time bidirectional interface with the nervous system. After several modifications, Fetz…
  • p. 22 …understand the brain, its regions of activity and how those area correlate to real time stimulation…
  • p. 25 …FOV=60x60mrn 7 • Experiment time=512 s. (B) (Top) Microelectrode array used in the study. (Bottom…
  • p. 28 …Movement times to target were on the order of 1-2 seconds with up to 75…
  • p. 29 …This trial lasted 3 months before the physical connection between the nerve and the microarray deteriorated…
  • p. 31 …Also beneficial to reaction time is the combined EMG EEG devices mentioned above since the pathways…
  • p. 32 …Proof of principle studies in this technology could emerge at any time, and given the demonstrated…
  • p. 34 …time. J Cogn Neurosci 2002 Nov 15; 14(8): 1200-14. " Hatsopoulos NG, Donoghue JP. The…
  • p. 36 …Targeted muscle reinnervation for real- time myoelectric control of multifunction artificial arms. JAMA 2009 Feb 11…
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localized in a manner where the top site will be below the cortical surface. The electrode
assembly was then wrapped with Gel Foam (Pfizer, Inc., New York) and then cemented
with dental acrylic (Reference 47). Once the experiment was concluded, precise location
of the cortical arrays was obtained by passing currents though the electrodes to cause
micro-lesioning, then post-mortem examination of brain slices could locate the lesions
and reconstruct the precise 3-D position of the electrodes (Figure 7). This test provided
an initial understanding of brain activity and the ability to utilize microelectrodes to
localize specific neural regions.
Sample slices from all implants
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Figure 7. Histology and Electrode Tracks. The left panel shows Nissl·stained coronal sections of sample slices
from all animals 01-04 showing electrode tracks or lesion marks for all seven implantations. The black line marks
the boundary between the upper and lower layers. The right panel shows seven coronal sections arranged rostro-
caudally, as indicated by the schematic, for one implant (D4Left) showing alternating lesions and electrode tracks
which were used to reconstruct site locations. (Reference 47)
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Report, from the dia collection. The PDF is mirrored here; the original link is under it. 36 pages are in the text index: search them above, or from the library's search.