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Defense Intelligence Reference Document Quantum Computing And Utilizing Organic Molecules In Automation Technology

Defense Intelligence Agency · 54 pages · text from the file's own layer

This Defense Intelligence Reference Document from the Defense Intelligence Agency, dated 10 December 2010, is one of a series of advanced technology reports produced in FY 2010 under the Advanced Aerospace Weapon System Applications (AAWSA) Program. It reviews quantum computing technologies and DNA-based molecular computing for onboard supercomputing on future spacecraft. It forecasts ion-trap quantum computers within 10 years, simple DNA tile computing within 20 years, and self-repairing DNA computers on a 40-year horizon.

  • p. 4 …A DNA nanomachine driven by repeated sequential addition of DNA control strands .............................................................................................................. 23 Figure 10. Recombinant…
  • p. 5 …protein molecule decorated with three legs--single-stranded DNAzymes, synthetic DNA molecules that act as enzymes…
  • p. 24 …Set strand ( ·open' \ Waste \ ( 'Closed' Unset strand Figure 9. A DNA nanomachine driven by repeated sequential…
  • p. 25 …Customized strand lengths or oligonucleotides (strands typically 100-200 base pairs long) can be easily ordered…
  • p. 26 …Assembly of DNA motifs with the aid of various branched DNA strands with sticky ends can…
  • p. 27 …This assembly method displaces one DNA strand and selectively replaces it with a strong complementary strand…
  • p. 30 …In this technique, the protection strand is a single oligomer that covers the input side of…
  • p. 32 …1) Single-strand DNAs are immobilized on the surface of a reaction chamber. This provides scaffolds…
  • p. 33 …Single-stranded origami such as William Shih's octahedron (113) cannot, by definition, suffer from this…
  • p. 34 …To hold the scaffold in this shape, helper strands are added to create a regular pattern…
  • p. 36 …In this latest case of DNA computing, inputs are replaced by single-stranded molecules, and how…
  • p. 42 …successive reversible branch migrations of DNA strands, and these strands were called "fuel" and "anti-fuel…
  • p. 45 …protein molecule decorated with three legs--single-stranded DNAzymes, synthetic DNA molecules that act as enzymes…
  • p. 46 …a, The NICK3.4A311 spider consists of a streptavidin core, with a 20-base single-stranded…
  • p. 53 …A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron. Nature, 427(6453…
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82. Bath J. and Turberfield A.J. DNA nanomachines. Nature Nanotechnology, VOL 2 :
MAY 2007.
83. Watson JD, Crick FH. Molecular structure of nucleic acids; a structure for
deoxyribose nucleic acid. Nature. 1953 Apr 25;171(4356):737-8.
84. Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain-terminating inhibitors.
Proc Natl Acad Sci US A. 1977 Dec;74(12):5463-7.
85.Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich HA, et al. Enzymatic
amplification of beta-globin genomic sequences and restriction site analysis for
diagnosis of sickle cell anemia. Science. 1985 Dec 20;230(4732):1350-4.
86. Mao, C and Yu, H. Growing millimeter-sized DNA crystals. SPIE Newsroom, April
2006.
87.Seeman NC. Nucleic acid junctions and lattices J. Theor. Biol. 99 237-47, 1982.
88.Seeman, N. C. De novo design of sequences for nucleic acid structural engineering.
l. Biomol. Struct. Dyns 8, 573-581, 1990.
89.Carbone A., Seeman NC. Molecular Tiling and DNA Self-assembly. Aspects of
Molecular Computing. 61-83,
90.Winfree E, Yang X, Seeman NC (1998b) Universal computation via self-assembly of
DNA: Some theory and experiments. In: Landweber LF, Baum EB, editors. DNA-
based computers II. Providence, Rhode Island: American Mathematical Society. pp.
191-213.
91. Winfree E Simulations of computing by self-assembly. Technical report CS-
TR: 1998.22. Pasadena, California: California Institute of Technology. 1998.
92. Wang H. Proving theorems by pattern recognition II. Bell System Tech J 40: 1-42,
1961.
93. Wang H An unsolvable problem on dominoes. Technical report BL-30 (II-15).
Cambridge, Massachusetts: Harvard Computation Laboratory.1962.
94. Winfree E., Liu F., Wenzler LA, Seeman NC. Design and Self-Assembly of Two-
Dimensional DNA Crystals, Nature, VDL 394 6 AUGUST, 1998.
95. Winfree, E. Algorithmic Self-Assembly of DNA: Theoretical Motivations and 2D
Assembly Experiments. Journal of Biomolecular Structure and Dynamics 11: 263-
270, 2000.
96. Winfree E. and Bekbolatov R. Proofreading tile sets: Error correction for algorithmic
self-assembly. In Proceedings of the Ninth International Meeting on DNA Based
Computers. Madison, Wisconsin, June 2003.
97.Reif, J.H., Sahu, S. and Yin, P. "Compact Error-Resilient Computational DNA Tilings,"
Nanotechnology Science and Computation (Chen, J. et al. Eds.), Springer-Verlag,
Berlin Heidelberg, pp. 79-103, 2006.
98. Fujibayashi, K., Murata, S. "A method of error suppression for self-assembling DNA
tiles," DNA Computing 10 (Ferretti et al. Eds.), LNCS 3384, Springer- Verlag Berlin
Heidelberg, pp. 113-127, 2005.
99. Fujibayashi, Yu Zhang D., Winfree E., Murata S. Error Suppression Mechanisms for
DNA Tile Self-Assembly and their Simulations. Nat Comput. Springer, 2008.
100. Adleman, L.: Molecular Computation of Solutions to Combinatorial Problems,
Science, Vol.266, pp.1021-1024, 1994.
101. Winfree, E.: Algorithmic Self-Assembly of DNA, Ph.D Thesis, California Institute of
Technology, 1998.
102. Winfree, E., Yang, X. and Seeman, N. C.: Universal Computation via Self-assembly
of DNA : Some Theory and Experiments, DNA based Computers 2, DIMACS Series
in Discrete Mathematics and Theoretical Computer Science, Vol.44, pp.191-
213,1999.
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Report, from the dia collection. The PDF is mirrored here; the original link is under it. 54 pages are in the text index: search them above, or from the library's search.