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Defense Intelligence Reference Document Quantum Computing And Utilizing Organic Molecules In Automation Technology

Defense Intelligence Agency · 54 pages · text from the file's own layer

This Defense Intelligence Reference Document from the Defense Intelligence Agency, dated 10 December 2010, is one of a series of advanced technology reports produced in FY 2010 under the Advanced Aerospace Weapon System Applications (AAWSA) Program. It reviews quantum computing technologies and DNA-based molecular computing for onboard supercomputing on future spacecraft. It forecasts ion-trap quantum computers within 10 years, simple DNA tile computing within 20 years, and self-repairing DNA computers on a 40-year horizon.

  • p. 4 …A DNA nanomachine driven by repeated sequential addition of DNA control strands .............................................................................................................. 23 Figure 10. Recombinant…
  • p. 5 …protein molecule decorated with three legs--single-stranded DNAzymes, synthetic DNA molecules that act as enzymes…
  • p. 24 …Set strand ( ·open' \ Waste \ ( 'Closed' Unset strand Figure 9. A DNA nanomachine driven by repeated sequential…
  • p. 25 …Customized strand lengths or oligonucleotides (strands typically 100-200 base pairs long) can be easily ordered…
  • p. 26 …Assembly of DNA motifs with the aid of various branched DNA strands with sticky ends can…
  • p. 27 …This assembly method displaces one DNA strand and selectively replaces it with a strong complementary strand…
  • p. 30 …In this technique, the protection strand is a single oligomer that covers the input side of…
  • p. 32 …1) Single-strand DNAs are immobilized on the surface of a reaction chamber. This provides scaffolds…
  • p. 33 …Single-stranded origami such as William Shih's octahedron (113) cannot, by definition, suffer from this…
  • p. 34 …To hold the scaffold in this shape, helper strands are added to create a regular pattern…
  • p. 36 …In this latest case of DNA computing, inputs are replaced by single-stranded molecules, and how…
  • p. 42 …successive reversible branch migrations of DNA strands, and these strands were called "fuel" and "anti-fuel…
  • p. 45 …protein molecule decorated with three legs--single-stranded DNAzymes, synthetic DNA molecules that act as enzymes…
  • p. 46 …a, The NICK3.4A311 spider consists of a streptavidin core, with a 20-base single-stranded…
  • p. 53 …A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron. Nature, 427(6453…
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the complementary binding of the Watson-Crick base pairs that correspond to each sticky
end. In this way, a lattice structure can be built upon the base structure by synthesizing
additional DX motifs to construct what is known as a "DNA tile." These tiles can be further
utilized as a scaffold for additional molecular structures.
In order to envision the aTAM tiling process, it is easy to picture various tiles with different
numbers written on the sides, indicating matching rules where two tiles would stick only if
their contacts matched. Additional matching interactions can be arranged in a manner that
adjacent tiles can strongly hold the next one in place, but a single interaction creates a weak
bond. Figure 12 illustrates an instantiation of the algorithmic self assembly process, in which
sets of four species tiles that represents XOR (exclusive OR) function to create a Sierpinski
triangle pattern. The so called seed structure is used to input the initial values that
commence the algorithmic self assembly process. However, it must be noted that random
nucleation events may occur. Nevertheless, algorithmic self-assembly has created a means
to emulate cellular automata.
27
A I = 1
I= I
I = 0
I I I I I I
B CJ
X I y
C !IC'""'"""""":)l Oc------"_:1 l~l I~
-~· a..._____s ,l...:.:'.'.:..s ~.
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Figure 12. (top a-e) The XOR Cellular Automaton and Its Implementation by Tile-Based Self-Assembly.
(bottom a-e) AFM Images of Algorithmic Self-assembly of Sierpinski Triangle Crystals.
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Report, from the dia collection. The PDF is mirrored here; the original link is under it. 54 pages are in the text index: search them above, or from the library's search.