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Defense Intelligence Reference Document Quantum Computing And Utilizing Organic Molecules In Automation Technology

Defense Intelligence Agency · 54 pages · text from the file's own layer

This Defense Intelligence Reference Document from the Defense Intelligence Agency, dated 10 December 2010, is one of a series of advanced technology reports produced in FY 2010 under the Advanced Aerospace Weapon System Applications (AAWSA) Program. It reviews quantum computing technologies and DNA-based molecular computing for onboard supercomputing on future spacecraft. It forecasts ion-trap quantum computers within 10 years, simple DNA tile computing within 20 years, and self-repairing DNA computers on a 40-year horizon.

  • p. 4 …A DNA nanomachine driven by repeated sequential addition of DNA control strands .............................................................................................................. 23 Figure 10. Recombinant…
  • p. 5 …protein molecule decorated with three legs--single-stranded DNAzymes, synthetic DNA molecules that act as enzymes…
  • p. 24 …Set strand ( ·open' \ Waste \ ( 'Closed' Unset strand Figure 9. A DNA nanomachine driven by repeated sequential…
  • p. 25 …Customized strand lengths or oligonucleotides (strands typically 100-200 base pairs long) can be easily ordered…
  • p. 26 …Assembly of DNA motifs with the aid of various branched DNA strands with sticky ends can…
  • p. 27 …This assembly method displaces one DNA strand and selectively replaces it with a strong complementary strand…
  • p. 30 …In this technique, the protection strand is a single oligomer that covers the input side of…
  • p. 32 …1) Single-strand DNAs are immobilized on the surface of a reaction chamber. This provides scaffolds…
  • p. 33 …Single-stranded origami such as William Shih's octahedron (113) cannot, by definition, suffer from this…
  • p. 34 …To hold the scaffold in this shape, helper strands are added to create a regular pattern…
  • p. 36 …In this latest case of DNA computing, inputs are replaced by single-stranded molecules, and how…
  • p. 42 …successive reversible branch migrations of DNA strands, and these strands were called "fuel" and "anti-fuel…
  • p. 45 …protein molecule decorated with three legs--single-stranded DNAzymes, synthetic DNA molecules that act as enzymes…
  • p. 46 …a, The NICK3.4A311 spider consists of a streptavidin core, with a 20-base single-stranded…
  • p. 53 …A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron. Nature, 427(6453…
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overhangs at the end of the double helix (Figure 10). These fragments can be exploited to
create a recombinant molecule of DNA by;
a. Inserting or removing a specific sequence of DNA.
b. Attaching a fluorescent molecular beacon.
c. Amplifying the sequence through the PCR process.
l
A Ar l C
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Figure 10. Recombinant DNA molecule with restriction enzyme cleavage and sticky end ligation.
7. By carefully using the recombinant tools and technologies available to genetic engineers,
one can properly program a customized Watson-Crick base-paired DNA motif that will
self-assemble in solution. This method of self assembly is preferred on small scale
applications due to the difficulties experienced when assembling nanoscale objects
through the traditional top down method. Assembly of DNA motifs with the aid of various
branched DNA strands with sticky ends can be directed by the geometry and connectivity
of the varying motifs. Once the structure is assembled a range of DNA lattices can be
produced (Figure 11).
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Report, from the dia collection. The PDF is mirrored here; the original link is under it. 54 pages are in the text index: search them above, or from the library's search.