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This Defense Intelligence Agency reference document, dated 7 January 2010 and prepared under the Acquisition Threat Support series, surveys biomaterials used in medicine. It covers biocompatibility, biosensor membranes, silicones, Teflon, biodegradable polymers, hydrogels, titanium, bioceramics, tissue constructs, cardiovascular stents, contact lenses, drug delivery and dialysis. It concludes that biomaterial performance underlies many medical devices, that the industry is slow to adopt new materials because of testing costs, and that innovation mainly involves new applications of established materials.
“The Times”8 pages
UNCLASSIFIEDf/liOA 8FFIGl•.L W&E 8tllalJ Contents Introduction ............................................................................................................. vi Imp.ortance of Biocompatlbll1ty ........................................................11:~•········· .................. vii Science of Biomaterials .....................................................................................vii Blomaterlals for Biosensors ····"··················· ....................~ ••••••••••••••••••••••••••••••••••••••• 1 Biomaterials for Biomedicine ................................................................................. 2 iv Biomedical Silicones - Polydimethylsiloxanes .................................................... 2 Silicone Chemistry ..........................................•....................................•................ 4 Silicone In Blomedlcal Products ........................................................•................. 4 Teflon .................................................................................................................. & Biodegradable Po.lymers ................... ~··· ................................................................... 7 Biodegradation Advantages.................................................................................. 8 Degradable Biomaterials .............................................................................................................. 8 Polylactic Acid and Polyglycolic Acid .................................................................. 8 Polyethylene Glycol or Polyethylene Oxide ........................................................ 10 Hydrogels ............................................................................................................................................................................ 1 o Titanium - Hip and Knee Joints 11 BioCeramics ................................................................................................................................................................. 11 Denta.1 ceramics .................. IIIJl•IIIJI ....................................................................................................................................................... 13 Tissue Constructs as Biomaterials ......................................................................................................................... 13 Cardiovascular Blomaterlals ...................................................................................................................._..15 Stent Biomaterials .......................................................................................: ................................................... _ts Nltlnol as a Blomaterlal ............................, ........................................................................ 19 Conta·ct Lenses ........................................................................................................................................ 19 Drug Del Ivery- Polymers.......... .,.......................................................................................■ Ill. 20 Medical Titanium as a Biomaterial ....................................................................................................... 22 UNCLASSIFIED 1 1 1i09 QSliICif P j ' 1155 ARP! X
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Report, from the dia collection. The PDF is mirrored here; the original link is under it. 32 pages are in the text index: search them above, or from the library's search.