(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

LD50 180.0 -56.0-560.0- MED50 3.2 -1.0-10.0- RATIO LD50/MED50 56.0 STATE SOLID INTRAVENOUS TOXICITY TO MICE DOSE MG/KG DILUT ML/KG REACT. FRACT. REACTION SIGN MIN. APPR DEG= REE MIN. TO RECOVER 320.0 32.0 2/2 DEATH 74 0 100.0 10.0 1/2 INC LOCOMOTOR ACTIVITY 224 0 * 100.0 10.0 2/2 DEC LOCOMOTOR ACTIVITY 124 0 *** 100.0 10.0 1/2 CIRCLING MOVEMENTS 025 0 100.0 10.0 2/2 DEC SENSITIVITY TO PAIN 229 8 100.0 10.0 2/2 DEC SENSITIVITY TO SOUND 230 0 * 100.0 10.0 2/2 DEC SENSITIVITY TO TOUCH 231 8 * 100.0 10.0 2/2 PINNAL REFLEX DEPR 331 8 * 100.0 10.0 2/2 SOCIAL INTERACTION ALTERED 132 0 100.0 10.0 2/2 DEC REARING FREQUENCY 632 0 100.0 10.0 1/2 STRAUB TAIL 233 0 100.0 10.0 1/2 LIMP TAIL 333 0 100.0 10.0 1/2 ATAXIA 35 0 *** 100.0 10.0 2/2 DEC PREENING 240 0 100.0 10.0 1/2 LOW POSTURE 241 0 100.0 10.0 1/2 EXTENSION OF LIMBS 341 0 100.0 10.0 1/2 RIGHTING REFLEX DEPR 742 0 100.0 10.0 2/2 EYELID PTOSIS-NONPARALYTIC 149 60 *** 100.0 10.0 2/2 PUPILLARY LIGHT REFLEX ABS 152 8 100.0 10.0 2/2 MYDRIASIS 154 8 *