(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

LD50 100.0 -32.0-320.0- MED50 18.0 -5.6-56.0- RATIO LD50/MED50 6.0 STATE SOLID INTRAVENOUS TOXICITY TO MICE DOSE MG/KG DILUT ML/KG REACT. FRACT. REACTION SIGN MIN. APPR DEG- REE MIN. TO RECOVER 320.0 32.0 2/2 DEATH 74 0 100.0 10.0 1/2 DEATH 74 0 100.0 10.0 1/2 DEC LOCOMOTOR ACTIVITY 124 0 *** G 300 100.0 10.0 1/2 DEC REARING FREQUENCY 332 0 G 300 100.0 10.0 1/2 EYELID PTOSIS-NONPARALYTIC 149 8 * 300 100.0 10.0 1/2 INC RESPIRATORY DEPTH 161 8 G 300 100.0 10.0 1/2 DEC RESPIRATORY RATE 262 8 G 300 100.0 10.0 1/2 IRREGULAR RESPIRATORY RATE 362 15 300 100.0 10.0 1/2 MOT DEF HORIZONTAL STRIP 471 30 * 300 100.0 10.0 1/2 MOT DEF ROTA-RCD 771 30 * 300 100.0 10.0 1/2 MOT DEF INCLINED STRIP 671 30 * 300 100.0 10.0 1/2 LOW CARRIAGE 175 0 240 32.0 3.2 2/2 EYELID PTOSIS-NONPARALYTIC 149 30 - * 300 32.0 3.2 1/2 INC RESPIRATORY DEPTH 161 15 240 32.0 3.2 1/2 DEC RESPIRATORY RATE 262 15 240 32.0 3.2 1/2 IRREGULAR RESPIRATORY RATE 362 15 240 10.0 10.0 2/2 NO EFFECT 73 DIL. 0.5% M.C. SUSP QS C H2O [redacted] 66