LD50 180.0 -56.0-560.0-
MED50 0.018-5.6-3-0.056-
RATIO LD50/MED50 10,000
STATE SOLID
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INTRAVENOUS TOXICITY TO MICE
DOSE MG/KG
DILUT ML/KG
REACT. FRACT.
REACTION SIGN
MIN. APPR
DEG= REE
MIN. TO RECOVER
320.0
32.0
2/2
DEATH
74
0
100.0
10.0
2/2
DEC LOCOMOTOR ACTIVITY
124
0
*** 300
100.0
10.0
1/2
INC SENSITIVITY TO TOUCH
131
30
* G 300
100.0
10.0
2/2
SOCIAL INTERACTION ALTERED
132
0
G 300
100.0
10.0
2/2
DEC REARING FREQUENCY
632
0
G 300
100.0
10.0
2/2
SUB-CONVULSIVE MOVEMENTS
436
15
60
100.0
10.0
2/2
LOW POSTURE
241
15
120
100.0
10.0
2/2
TREMORS=REST AND MOVEMENT
144
0
* 120
100.0
10.0
2/2
EYELID PTOSIS=NONPARALYTIC
149
30
*** G 300
100.0
10.0
1/2
PUPILLARY LIGHT REFLEX ABS
152
8
200
100.0
10.0
1/2
MYDRIASIS
154
8
* 200
100.0
10.0
2/2
HEMATURIA
358
15
200
100.0
10.0
2/2
INC RESPIRATORY DEPTH
161
0
120
100.0
10.0
2/2
IRREGULAR RESPIRATORY DEPTH
361
0
120
100.0
10.0
2/2
DEC RESPIRATORY RATE
262
0
120
100.0
10.0
2/2
IRREGULAR RESPIRATORY RATE
362
0
120
100.0
10.0
1/2
MOT DEF VERTICAL ROD
371
8
* G 300
32.0
3.2
2/2
DEC LOCOMOTOR ACTIVITY
124
60
* 120
32.0
3.2
2/2
TREMORS=REST AND MOVEMENT
144
0
* 60
[redacted]
50