LD50 56.0 =18.0=130.0=
MED50 3.2=3=1.0=3=1.0=3=
RATIO LD50/MED50 175,000
STATE SOLID
INTRAVENOUS TOXICITY TO MICE
DOSE MG/KG
DILUT ML/KG
REACT. FRACT.
REACTION SIGN
MIN. APPR
DEG-REE
MIN. TO RECOVER
100.0
10.0
2/2
DEATH
74
0
32.0
3.2
2/2
DEC LOCOMOTOR ACTIVITY
124
30
*
240
32.0
3.2
2/2
INC SENSITIVITY TO TOUCH
131
60
*
240
32.0
3.2
2/2
PINNAL REFLEX DEPR
331
30
*
60
32.0
3.2
2/2
HEAD TWITCH
531
60
*
120
32.0
3.2
2/2
SOCIAL INTERACTION ALTERED
132
0
240
32.0
3.2
2/2
DEC REARING FREQUENCY
632
30
240
32.0
3.2
2/2
TREMORS-REST AND MOVEMENT
144
0
*
120
32.0
3.2
2/2
INC RESPIRATORY DEPTH
161
0
60
32.0
3.2
1/2
DEC RESPIRATORY DEPTH
261
8
60
32.0
3.2
2/2
INC RESPIRATORY RATE
162
0
*
3
32.0
3.2
1/2
DEC RESPIRATORY RATE
262
15
60
32.0
3.2
2/2
IRREGULAR RESPIRATORY RATE
362
15
-
60
32.0
3.2
2/2
RESTLESSNESS
79
30
180
10.0
10.0
2/2
INC LOCOMOTOR ACTIVITY
224
60
*
120
10.0
10.0
2/2
DEC LOCOMOTOR ACTIVITY
124
120
*
240
10.0
10.0
2/2
INC SENSITIVITY TO TOUCH
131
60
*
240
10.0
10.0
2/2
SOCIAL INTERACTION ALTERED
132
0
240
10.0
10.0
2/2
TREMORS-REST AND MOVEMENT
144
0
*
120
47