(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

EFFECT OF COMPOUNDS ON BLOOD PRESSURE, HEART RATE AND RESPIRATION AFTER ADMINISTRATION TO CHLORALOSSED CATS (Contd) Compound Dose mg/kg Change in Mean Blood Pressure mm Hg Change in Heart Rate beats/min Respiration Remarks 9346-63 1.0 .10 0 0 3.3 -30 +42 0 9346-85 0.3 0 0 0 1.0 0 0 0 3.3 0 0 0 9346-87 0.3 0* 0* 0* Decrease in blood pressure not blocked by atropine. Response to norepinephrine and tyramine may have been enhanced. 1.0 0* 0* 0* 3.3 -35* 0* 0* 3.3 -40 0 0 9405-13 0.3 0 0 Increased depth 3.3 -67 0 Increased depth 9405-21 1.0 0 0 0 EKG voltage increased 3.3 0 0 0 EKG voltage increased 10.0 -10 +18 0 EKG voltage increased 9405-33 0.3 0 0 0 1.0 0 0 0 3.3 0 +30 0 PAGE 4