(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

OBSERVATIONS CAT NO. DOSE WT. TIME AND SEX MG/KG KG. HOURS PERIPHERAL SENSATION QUESTIONABLE = NO RESPONSE TO NEEDLE PRICKS 53 F 9.2 EXTENSOR THRUST REFLEXES ABSENT HIND LIMBS HOPPING REACTION ABSENT IN INJECTED FOOT GROWLING WHEN HANDLED LYING ON SIDE. BUT CAN STAND OTHER NEUROLOGICAL TESTS NORMAL HEART RATE 138 BEATS/MINUTE RESPIRATIONS PER MINUTE 138 BODY TEMPERATURE C 38.5 NOSE COOL AND MOIST REDUCED ANAL TENSION LYING ON SIDE. BUT CAN STAND PANTING GROWLING WHEN HANDLED NEUROLOGICAL EXAMINATION NOT DONE SOLUTION = 20 % "TWEEN-20"